PSORIASIS A CHRONIC, NON-CONTAGIOUS AUTOIMMUNE DISEASE:
A CONVENTIONAL TREATMENT
Shivanand Pandey*
Email: dot.shivanand@gmail.com
Psoriasis is a chronic, non-contagious autoimmune disease that affects the skin and joints. It commonly causes red, scaly patches to appear on the skin. The disadvantages of topical agents are variably that they can often irritate normal skin, can be time consuming and awkward to apply, cannot be used for long periods, can stain clothing or have a strong odor. As a result, it is sometimes difficult for people to maintain the regular application of these medications. Abrupt withdrawal of some topical agents, particularly corticosteroids, can cause an aggressive recurrence of the condition. This is known as a rebound of the condition. While alternative like spa, balneo, ischyotherapy takes long time consuming, TNF- α blockers have the potential to provide symptomatic relief and help prevent disease progression in PsA. Although these drugs are relatively expensive, concerns over an increased drug budget must be balanced against the potential long-term cost savings. At the present time there are no health economic studies concerning the role of TNF- α blockade in PsA. However, possible long- term benefits include: reduced need for joint replacement surgery, reduced demand on therapy services, reduced demands on medical and nursing services, reduced needs for other medicines, reduced demands on social services and carers, improved quality of life, improved prospect of remaining in work, increased life expectancy.
Keywords: Psoriasis, autoimmune disease, corticosteroids, TNF- α blockers.
Volume 1, Issue 2, March – April 2010; Article 012 ISSN 0976 – 044X
International Journal of Pharmaceutical Sciences Review and Research Page 61
Available online at www.globalresearchonline.net
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